The Benedict Cassen Prize is awarded in recognition of outstanding achievement and work leading to a major advance in nuclear medicine science. The prize award is $25,000 and is only offered every other year (even years).

This prestigious prize is named in honor of the late physicist Benedict Cassen, whose invention, the rectilinear scanner, first brought the ability to image patients to nuclear medicine. His widow, Mary Wylie Cassen, made a bequest to the Foundation to establish a major award. The awarding of this prize is in recognition of outstanding achievement is essential to encourage development and growth in nuclear medicine.

Award Recipients

1994 – Hal O. Anger, B.S., D.Sc. (Hon.), for his invention of the scintillation camera.

1996 – David E. Kuhl, M.D., for his development of emission reconstruction tomography and quantitative measurements of brain physiology.

1998 – Henry N. Wagner, Jr., M.D., for his many contributions to Nuclear Medicine as a scientist, teacher and clinician.

2000 – Sally J. DeNardo, M.D., and Gerald L. DeNardo, M.D., for their fundamental contributions to present and future medical care through work in developing radiolabelled antibodies and contributions to the radioimmunotherapy of cancer.

2002 – Michael E. Phelps, PhD., for his exceptional involvement and work to translate PET science into clinical medical practice.

2004 – Michael J. Welch, PhD., for his work on rapid synthesis of positron-labeled organic chemicals which were of vital importance in the application of PET technology’s application to diagnostic medicine.

2006 – Alexander Gottschalk, M.D., for his pioneer work in the clinical applications of the Anger gamma camera and the use of Technetium radiotracers.

2008 – Mathew Thakur, PhD., for his original and major advances in the development of novel radiopharmaceuticals that have led nuclear medicine to play a major role in the management of patients with infections, vascular thromboembolism, and cancer.

2010 – Sung-Cheng (Henry) Huang, D.Sc., for his scholarship in applying biomathematics to the development & application of tracer kinetic models used as imaging assays of biological process in vivo with PET, from basic to clinical sciences.

2012 – Abass Alavi, MD, MD(Hon), PhD(Hon), DSc(Hon), for his contributions to the development of modern imaging techniques including Positron Emission Tomography, as revolutionary tools for conducting basic science research and improving patient care.

2012 – Steven M. Larson, M.D., for his research and leadership that have advanced nuclear medicine science, especially in uses of radionuclides for diagnosis and treatment of cancer.

2014 – Barry A. Siegel, M.D., for his sustained contributions to clinical translation of nuclear medicine science and, in particular, his visionary leadership in developing scientific methodology for evidence-based clinical trials that resulted in widespread acceptance of imaging studies using positron emission tomography.

2016 – H. William Strauss, M.D., in recognition of his seminal studies in cardiovascular nuclear medicine. These studies have greatly advanced nuclear medicine science and have had exceptionally high clinical impact.

2018 – Sanjiv Sam Gambhir, M.D., Ph.D., in recognition of his visionary leadership and rigorous science in developing and translating strategies for the imaging of human diseases using novel multimodality reporter genes and imaging agents.

2020 – Peter S. Conti, MD, PhD, in recognition of his pioneering work in the development of novel radiopharmaceuticals and clinical PET applications for cancer imaging, as well as his volunteerism and service to the molecular imaging community.

The Benedict Cassen Postdoctoral Fellowship  
This grant was established by the Estates of Benedict Cassen and Mary Wiley Balfour Cassen to provide early-career scientists with mentoring experience and the opportunity to develop preliminary data for federal or other competitive research support. The grant will provide support for the postdoctoral fellow to carry out the research under the supervision of the junior faculty member with the assistance of a senior faculty member or principal investigator.

2014 – Marc David Normandin, PhD, Instructor of Radiology, Harvard Medical School Assistant in Physics, Massachusetts General Hospital, Department of Radiology.

Georges El Fakhri, PhD, DABR, Director, Center for Advanced Medical Imaging Sciences (CAMIS), Co-Director, Division of Nuclear Medicine & Molecular Imaging, Professor of Radiology Harvard Medical School is Dr. Normandin’s advisor.

2015 – Kyle Lapidus, MD, PhD, Assistant Professor, Director of Neuromodulation, Stony Brook University, Department of Psychiatry.

Ramin Parsey, MD, PhD, Professor and Chair of the Department of Psychiatry, Director of PET Research, Stoney Brook School of Medicine, is advisor to Dr. Lapidus.

2018 – Amy M. Fowler, M.D., Ph.D., University of Wisconsin, School of Medicine and Public Health, Department of Radiology, Breast Imaging Section

Jamey Weichert, PhD, Associate Professor in the Department of Radiology and Director of the UW-Madison Contrast Agent Laboratory is Dr. Fowler’s advisor.

NET RF/ERF Nuclear Medicine Pilot Research Grant

2016 Thomas A. Hope, MD, for “Intra-Arterial Peptide Receptor Radionuclide Therapy (IA-PRRT) using 90Y-DOTA-TOC.”

2017 Babak Behnam Azad, PhD, for “An improved approach for detection and therapeutic monitoring of neuroendocrine tumors by PET.”

2018 Tara E. Mastren, PhD, for “Functionalized Silica Nanoparticles: Development of a Combined PET and TAT Theranostic Agent for Neuroendocrine Tumors.”

2019 Susanne Kossatz, PhD, for “Uncovering the cellular mechanisms that limit clinical application of PRRT.”

The Drs. Tapan K. Chaudhuri And Tuhin K. Chaudhuri Award For Best SNMMI Abstract In Breast Cancer Research
Heather Jacene for“Imaging Androgen Receptors in Breast Cancer with 18F-fluoro-5α-dihydrotestosterone-PET: A Pilot Study”

Bradley-Alavi Student Fellowships
Yanson Zhu
Zachary Rosenkrans
Matthew Dilsizian

Paul C. Aebersold, PhD Award
Carolyn Anderson, PhD

ERF SNMMI Medical Science Student Research Grant
Philip Manes
Catherine Meyer
Peng Lu
Zekun Li
Amy Zhang

Susan C. Weiss Clinical Advancement Scholarship
Nickie Beaulieu

ERF SNMMI-TS Bachelor’s or Master’s degree Completion Scholarship
Jordan Jayne
Sarah Gibbons

ERF SNMMI-TS Advanced Degree Scholarship
Mary Beth Farrell

SNMMI-TS/ERF Outstanding Technologist
Matthew C. McMahon, MS, CNMT, RT(CT)

SNMMI-TS/ERF Outstanding Educator
Geoffrey M. Currie, PhD BPharm MMRS CNMT

ERF SNMMI Journal of Nuclear Medicine Best Paper
Carola Focke

ERF SNMMI Journal of Nuclear Medicine Technologist Best PaperSarah Frye
Jena-Lee McKee
Audrey B. Davis

Paul Cole Technologist Scholarship
Rafat Mohamed
Kye Broom
Jean Pierre Alfonso
Amanda Lima
Alannah Macaulay
Desiree Dinko
Alexandra Herman
Jordan Gottsacke
rSheryl Dekker
Mckenzie Wills

2020 ERF-SNMMI Young Investigator Awards
Inga Melvinsdottir
Jakub Toczek
Nele Inga Hermanns
Mingkai Yun
Yuka Otaki
Jacek Kwiecinski
Iris Zhou
Tomomi Nobashi
Carolina Ferreira
Haewook Park
Zhaoheng Xie
Martin Lyngby Lassen
Katherine Lucot
Matthew Zammit
Merle Hoenig
Ian Duffy
Outi Keinaenen
Rocio Garcia Vazquez
Diane S. Abou
Reinier Hernandez, PhD
Edward O’Neill

Technologist Best Oral Abstract
Michelle Gruhot
Chelsey Wacholz
Katie Moses

Technologist Best Poster Award
Ashlee Stanke
Sarah Frye
Jeanan Al-Mabuk

Alavi–Mandell Awards

Parameters to predict progression free and overall survival after peptide receptor radionuclide therapy: a multivariate analysis in 782 patients
Else Aalbersberg

Early experience of rechallenge 177Lu-PSMA radioligand therapy after an initial good response in patients with mCRPC
Andrei Gafita

qPSMA: a semi-automatic software for whole-body tumor burden assessment in prostate cancer using 68Ga-PSMA11 PET/CT
Andrei Gafita

A prospective observational study to evaluate the effects of long-acting somatostatin analogs on 68Ga-DOTATATE uptake in patients with neuroendocrine tumors
Anni Gålne

Preclinical Evaluation of a Radiofluorinated Benzazepine Derivative for Imaging the GluN2B Subunit of the Ionotropic NMDA Receptor
Ahmed Haider

Preclinical Evaluation of Benzazepine-Based PET Radioligands (R)– and (S)– 11C-Me-NB1 Reveals Distinct Enantiomeric Binding Patterns and Tightrope Walk between GluN2B- and Sigma1 Receptor-Targeted PET Imaging
Ahmed Haider

Preclinical Evaluation of 111In-labeled PEGylated Maytansine Nimotuzumab Drug Conjugates in EGFR-positive Cancer Models
Siddesh Hartimath

Tumor lysis syndrome: a rare, but serious complication of radioligand therapies
Kai Huang

Generation of PET attenuation map for whole-body time-of-flight 18F-FDG PET/MRI using a deep neural network trained with simultaneously reconstructed activity and attenuation maps
Donghwi Hwang

F-18 FDG PET/CT for monitoring of ipilimumab therapy in patients with metastatic melanoma
Kimiteru Ito

Healthy Tissue Uptake of 68Ga-Prostate Specific Membrane Antigen (PSMA), 18F-DCFPyL, 18F-Fluoromethylcholine (FCH) and 18F-Dihydrotestosterone (FDHT)
Bernard Jansen

Simplified Methods for Quantification of 18F-DCFPyL Uptake in Patients with Prostate Cancer
Bernard Jansen

89Zr-immuno-PET: towards a non-invasive clinical tool to measure target engagement of therapeutic antibodies in-vivo
Yvonne Jauw

Quantitative tumor perfusion imaging with 82Rubidium-PET/CT in prostate cancer -; analytical and clinical validation
Mads Jochumsen

Design of Cerenkov-assisted Photoactivation of TiO2 Nanoparticles and Reactive Oxygen Species Generation for Cancer Treatment
Shalinee Kavadiya

Albumin-Binding PSMA Ligands: Implications for Expanding the Therapeutic Window
James Kelly

Blocking Glucagon Like Peptide-1 Receptors in the Exocrine Pancreas Improves Specificity for Beta Cells in a Mouse Model of Type 1 Diabetes
Eshita Khera

DOTA-MGS5, a new cholecystokinin-2 receptor targeting peptide analog with optimized targeting profile for theranostic use
Maximilian Klingler

Assessment of simplified methods for quantification of 18F-FDHT uptake in patients with metastatic castration-resistant prostate cancer
Gerbrand Kramer

18F-Fluoroestradiol Positron Emission Tomography Imaging of Activating Estrogen Receptor Alpha Mutations in Breast Cancer
Manoj Kumar

One-step 18F-labeling and preclinical evaluation of prostate specific membrane antigen trifluoroborate probes for cancer imaging.
Hsiou-Ting Kuo

Three-hour delayed imaging improves assessment of coronary 18F-sodium fluoride PET
Jacek Kwiecinski

Data-driven gross patient motion detection and compensation: Implications for coronary 18F-NaF PET imaging
Martin Lyngby Lassen

Improving 68-Ga-PSMA PET/MR hybrid imaging of the prostate with un-renormalized absolute scatter correction
Maike Lindemann

Preclinical evaluation and pilot clinical study of Al18F-PSMA-BCH for prostate cancer imaging
Teli Liu

68Ga-pentixafor PET/CT for imaging of chemokine receptor-4 expression in Waldenstrom macroglobulinemia/lymphoplasmacytic lymphoma: comparison to 18F-FDG PET/CT
Yaping Luo

In vitro and in vivo characterization of a 18F-AlF-labeled PSMA ligand for imaging of PSMA-expressing xenografts
Susanne Lütje

Preclinical pharmacokinetics and dosimetry studies of [124I/131I]-CLR1404 for treatment of pediatric solid tumors in murine xenograft models
Ian Marsh

Side effects of CXC-chemokine receptor 4 -; directed Endoradiotherapy with Pentixather prior to Hematopoietic Stem Cell Transplantation
Sabine Maurer

Imaging chemotherapy induced acute cardiotoxicity with 18F-labelled lipophilic cations
Stuart McCluskey

Three dimensional tumor-margin demarcation using the hybrid tracer indocyanine green-99mTc-nanocolloid, a proof of concept study in tongue cancer patients scheduled for sentinel node biopsy
Philippa Meershoek

Evaluation of a novel elastic respiratory motion correction algorithm on quantification and image quality in abdomino-thoracic PET/CT
Joseph Meier

Metabolic Tumour Volume for Response Prediction in Advanced-Stage Hodgkin Lymphoma
Jasmin Mettler

Awake 18F-FDG PET imaging of memantine-induced brain activation and test-retest in freely running mice
Alan Miranda

Cerebral metabolic changes related to freezing of gait in Parkinson’s disease
Trina Mitchell

18F-branched chain amino acids: structure-activity relationships and PET imaging potential
Matthew Nodwell

Optimized feature extraction for radiomics analysis of 18F-FDG-PET imaging
Laszlo Papp

Evaluation of a novel PET radioligand to image O-GlcNAcase in brain and periphery of rhesus monkey and knock-out mouse.
Soumen Paul

Temporal Modulation of HER2 Membrane Availability Increases Pertuzumab Uptake and Pretargeted Molecular Imaging of Gastric Tumors
Patricia Pereira

Radiation dosimetry and biodistribution of 18F-PSMA-11 for PET imaging of prostate cancer
Sarah Piron

N-(2-(dimethylamino)ethyl)-4-18F-fluorobenzamide: A Novel Molecular Probe for High-Contrast PET Imaging of Malignant Melanoma
Ayoung Pyo

Production of 15O for medical applications via the 16O – 15O reaction
Stacy Queern

Dosimetry estimate and initial clinical experience with 90Y-PSMA-617.
Hendrik Rathke

PET/CT versus standard imaging for prediction of survival in patients with recurrent head and neck squamous cell carcinoma
Max Rohde

Multispectral optoacoustic tomography of benign and malignant thyroid disorders – a pilot study
Wolfgang Roll

Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second Generation Amyloid-beta Mouse Model
Christian Sacher

Sensitivity and Isoform Specificity of 18F-Fluorofuranylnorprogesterone for Measuring Progesterone Receptor Protein Response to Estradiol Challenge in Breast Cancer
Kelley Salem

Impact of 68Ga-PSMA-PET/CT on the radiotherapeutic approach for prostate cancer in comparison to CT -; a retrospective analysis
Nina-Sophie Schmidt-Hegemann

Outcome after PSMA PET/CT based salvage radiotherapy in patients with biochemical recurrence after radical prostatectomy: a bi-institutional retrospective analysis
Nina-Sophie Schmidt-Hegemann

Quantitative imaging biomarkers for Yttrium-90 distribution on Bremsstrahlung single photon emission computed tomography after resin-based radioembolization
Isabel Schobert

Dynamic 11C-PiB PET shows cerebrospinal fluid flow alterations in Alzheimer’s disease and multiple sclerosis
Julia Schubert

Intention to treat analysis of 68Ga-PSMA and 11C-choline PET/CT versus CT for prostate cancer recurrences after surgery
Johannes Schwenck

Long-term effects of radioiodine treatment on salivary gland function in adult survivors of pediatric differentiated thyroid carcinoma
Tharsana Selvakumar

68Ga-DOTA-E[c(RGDfK)]2 Positron Emission Tomography Imaging of SHARPIN-Regulated Integrin Activity in Mice
Riikka Siitonen

Impact of 18F-PSMA-1007 uptake in prostate cancer using different peptide concentrations: preclinical PET/CT study in mice.
Fumihiko Soeda

Synthesis of patient-specific transmission image for PET attenuation correction for PET/MR imaging of the brain using a convolutional neural network
Karl Spuhler

A fully automatic technique for precise localization and quantification of Amyloid-β PET scans
Mouna Tahmi

Dixon-VIBE Deep Learning (DIVIDE) Pseudo-CT Synthesis for Pelvis PET/MR Attenuation Correction
Angel Torrado-Carvajal

What FDG-PET response-assessment method best predicts survival after curative-intent chemoradiation in non-small cell lung cancer (NSCLC): EORTC, PERCIST, Peter Mac or Deauville criteria?
Guy-Anne Turgeon

Accuracy of 18F-FDG PET/CT in predicting residual disease after neoadjuvant chemoradiotherapy for esophageal cancer
Maria Valkema

Metabolic subtyping of pheochromocytoma and paraganglioma by 18F -FDG pharmacokinetics using dynamic PET/CT scanning
Anouk van Berkel

A pilot study on hepatobiliary scintigraphy to monitor regional liver fucntion in yttrium-90 radioembolization
Sandra van der Velden

The Clinical Application of Fluorescence-Guided Surgery in Head and Neck Cancer
Stan van Keulen

Performance characteristics of the digital Biograph Vision PET/CT system
Joyce van Sluis

Molecular imaging of fibroblast activity after myocardial infarction using a 68Ga-labelled fibroblast activation protein inhibitor FAPI-04
Zohreh Varasteh

The Impact of FcγRI Binding on ImmunoPET
Delphine Vivier

Synergistic Effect of a Mesothelin Targeted Thorium-227 Conjugate in Combination with DNA Damage Response Inhibitors in Ovarian Cancer Xenograft Models
Katrine Wickstroem

PET imaging of PARP expression using [18F]olaparib
Thomas Wilson

Tumor imaging using radiolabelled matrix metalloproteinase-activated anthrax proteins
Mary-Ann Xavier

Hexokinase 2 is targetable for HK1 negative, HK2 positive tumors from a wide variety of tissues of origin
Shili Xu

Biodistribution, tumor detection and radiation dosimetry of F-18 5-Fluoro-2′-Deoxycytidine (18F-FdCyd) with Tetrahydrouridine in solid tumors
Colin Young

Advancing Targeted Radionuclide Therapy through the National Cancer Institute’s Small Business Innovation Research Pathway
Kaveh Zakeri

Peptide Receptor Radionuclide Therapy in Grade 3 Neuroendocrine Neoplasms: Safety and Survival Analysis in 69 Patients
Jingjing Zhang

177Lu-PSMA-617 radioligand therapy in metastatic castration-resistant prostate cancer patients with a single functioning kidney
Jingjing Zhang

Variability and repeatability of quantitative uptake metrics in [18F]FDG PET/CT imaging of non-small cell lung cancer: impact of segmentation method, uptake interval, and reconstruction protocol
Mingzan Zhuang